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TINOSAGISTERONE A

Year of first isolation:	2025
Formula:	C₂₇H₄₀O₈
Molecular weight:	492
Occurence in plants:
Tinospora cordifolia [Menispermaceae] »
Occurence in animals:

TINOSAGISTERONE A

STRUCTURE DESCRIPTORS

MASS SPECTRUM

HRESIMS (negative ion mode) m/z

491.2650 (M-H)^- (calcd 491.2650)

CARBON NMR

PROTON NMR

CD₃OD
01	42.0
02	70.0
03	73.4
04	27.2
05	135.1
06	144.3
07	181.3
08	126.4
09	164.9
10	42.6
11	23.6
12	35.0
13	40.6
14	54.6
15	218.0
16	39.0
17	48.6
18	27.3
19	21.6
20	78.0
21	20.9
22	77.9
23	27.5
24	42.0
25	71.3
26	28.9
27	29.9

CD₃OD
01-Ha	2.32 (dd, 14.3, 2.8)
01-Hb	1.32 (m)
02-Ha	4.00 (d, 4.2)
03-He	3.55 (dt, 12.3, 4.2)
04-Ha	3.16 (dd, 12.3, 4.2)
04-Hb	2.54 (t, 12.3)
05-H	-
07-H	-
09-H	-
11-Ha	2.48 (m)
11-Hb	2.41 (m)
12-Ha	1.62 (m)
12-Hb	1.57 (m)
14-H	3.70 (s)
15-Ha	-
15-Hb	-
16-Ha	2.76 (dd, 20.6, 10.6)
16-Hb	2.38 (m)
17-H	2.41 (m)
18-Me	1.48 (s)
19-Me	1.29 (s)
21-Me	1.34 (s)
22-H	3.59 (m)
23-Ha	1.64 (t, 12.3)
23-Hb	1.45 (m)
24-Ha	1.82 (dd, 11.6, 8.6)
24-Hb	1.46 (m)
26-Me	1.20 (s)
27-Me	1.22 (s)

PHYSICAL PROPERTIES

M.P.	— °C
[α]_D²⁰	+ 60.2 (c 0.1 ; MeOH)
IR (KBr) ν _max (cm^-1)	3413, 2968, 2923, 1730, 1624
UV (MeOH) λ _max (log ε)	198 nm (4.58) ;

CHROMATOGRAPHY

HPTLC
GLC
TLC
HPLC

BIOLOGICAL ACTIVITIES

REFERENCES

First isolation

YUAN, R.-Q. et al. (2025) Chemistry & Biodiversity https://doi.org/10.1002/cbdv.202501502

Permanent link to this datasheet: TINOSAGISTERONE A

see Important notice
© Université Pierre & Marie Curie, Paris 6, France
© Institute of Organic Chemistry and Biochemistry, Academy of Sciences, Prague, Czech Republic
© Institut National de la Recherche Agronomique, Versailles, France
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